A higher resolution for therapeutic development

We are an AI/ML leader with a mission to deliver precision therapies for every patient with fibrotic or autoimmune disease

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Our platform to pinpoint the cells and pathways driving immune disease - and how they evolve over time - to empower therapeutic development

Spatial-omics meets AI/ML innovation

We make sense of vast multimodal databases to reveal the true drivers of disease invisible to prior methods

Game-changing predictive power

We forecast how disease evolves and responds to treatment before a single patient is dosed

Building medicines at every step

Every insight feeds our in-house pipeline of precision biologics for the majority of patients that current therapies leave behind
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Science/Platform

ENSIGHT is fueled by purpose-driven AI/ML tools

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Science/Platform

Purpose-built AI/ML for understanding disease in 4D

Four dimensions of disease. One integrated platform.

EnsoDB full logoEnsoDB LogoPathoSignatures full logoPathoSignature Logocell2target full logocell2target LogoPatientSelection full logoPatient Selection LogoEnsoAI full logoEnsoAI Logo
EnsoDB full logo
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100% human data. Zero translational guesswork.

EnsoDB is our unique and proprietary database collating vast single-cell and spatial disease datasets across inflammation and immunity. It provides the scale and diversity of human data needed to train EnsoAI models capable of uncovering novel biology.

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EnsoDB Figure Diagram
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PathoSignatures full logo
PathoSignatures logo

Identify cellular culprits with confidence.

PathoSignatures synthesizes single-cell, spatial, and genetics data to rank pathogenic cell types and provide validation from multiple sources. This helps reduce risk and increase confidence in development decisions.

Diverse datasets

PathoSignatures figure
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No target is an island.

Cell 2 Target pinpoints cell-specific and combinatorial opportunities within 3D tissue contexts relevant to disease. This enables the identification of safer and more therapeutic molecules.

Expression

Heatmaps comparing expression of not-selected and selected receptors across various cell types and target cell.
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PatientSelection full logo
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The right therapy, matched to the right patient.

Patient Selection uses EnsoAI to stratify patients into biologically meaningful subgroups to inform both therapeutic and clinical design. Characterizing the variety in disease will be key to precision medicine evolving beyond 'one-size-fits-all' therapies.

Observed patient
subgroups

Six colored tissue sample slides arranged in two rows with a color-coded key for responder types below.

Prospective patient stratification

Diagram showing histology data transfer to spatial domains then training a neural network to classify responders.Diagram showing new patient data classified by a model into responder, partial responder, and non-responder categories.
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EnsoAI full logo
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The fourth dimension: disease over time.

The EnsoAI platform harnesses all our datasets to reveal how tissues evolve as disease progresses. These insights power predictive simulations of tissue evolution, treatment response, and in silico simulations, enabling smarter therapeutic development.

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Tissue sample with pink histology stain on left and EnsoAI domain color segmentation on right.

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Data point network colored from blue (healthy) to red (severe) showing disease phenotype spread.
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About Us

What sets Ensocell apart from the rest

Our work is guided by five key values that speak to our commitment to scientific integrity, rigour and unlocking progress through teamwork.

We are scientists driven to turn insight into ground-breaking medicines.

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Purpose-driven

We develop transformative new therapies for patients facing serious disease

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Curiosity

We are driven by scientific curiosity and tenacity

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Collaboration

We strive for excellence in exuection and achievement as one team

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Honest Communication

We are committed to meaningful dialogue, empathy, and intellectual humility

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Calculated Risks

We embrace bold ideas and take calculated risks

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Careers

Open Positions

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Senior Research Associate

Protein Biotherapeutics

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Cambridge, Cambridgeshire
6 months (Fixed-term)
Posted X days ago
Research Associate

Protein Biotherapeutics

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Cambridge, Cambridgeshire
6 months (Fixed-term)
Posted X days ago
Job Title

Department

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Cambridge, Cambridgeshire
6 months (Fixed-term)
Posted X days ago
Contact

Get in touch

We're here to collaborate.

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info@ensocell.com
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Eddeva (Building B920)
Babraham Research Campus
Cambridge, UKCB22 3AT
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